Alarmingly,
the rate of obesity in the United States continues to rise. To aid in
battling obesity, many individuals use low-calorie artificial
sweeteners as a substitute for high-calorie foods.
Sucralose
was accidentally discovered in 1976 by Tate & Lyle, a British
sugar company. A graduate student misunderstood a request for
“testing” of a chlorinated sugar as a request for “tasting.”
Sucralose
is 600 times sweeter than sugar and contains no calories. Sucralose
was approved by the FDA in 1998 for use in 15 food categories,
including a tabletop sweetener under the brand name Splenda. It is
used in beverages, chewing gum, frozen desserts, fruit juices, and
gelatins. In 1999, the FDA expanded its use as a general-purpose
sweetener in all foods.
Sucralose
is a sucrose molecule in which three of the hydroxyl groups have been
replaced by chlorine atoms. Although sucralose is made from table
sugar, it adds no calories because it is not digested in the body.
Most of the sucralose given orally to mice, rats, dogs, and humans
passes through the gastrointestinal tract and is eliminated.
Sucralose gives me the bubble guts :( |
Toxicology studies of sucralose show little effect. Cases studies have been reported on sucralose consumption and the increased incidence of migraines triggered by sucralose.
Many
of the studies on product safety have been conducted by companies
that produce these products and are not generally available to
consumers. A Medline search of publications from 2000 to 2008 using
the key words “artificial sweeteners,” “sweetening agents,”
“toxicity,” “toxicology,” “safety,” and “consumer
product safety” resulted in only one study available to readers of
primary product safety data. Groups that believe the safety of these
substances has not been demonstrated point to the length of studies,
sample sizes, and lack of controls.
Susceptible
populations for the potential deleterious effects of artificial
sweeteners include diabetics, children, pregnant women, women of
childbearing age, breastfeeding mothers, individuals with low seizure
thresholds, and individuals at risk for migraines.
The
use of artificial sweeteners remains controversial. Their consumption
has been shown to cause mild to serious side effects ranging from
nuisance headaches to potentially life-threatening cancer. Recent
reports of selected sweeteners suggest they are not efficacious in
weight loss and may promote weight gain. Because artificial
sweeteners are in more than 6,000 products, including foods,
medications, and cosmetics, it is impossible to completely eradicate
them from daily encounters.
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